Needle-free drug delivery can be realized using the principle of jet injection, whereby a liquid drug is pressurized and accelerated through a small orifice, creating a narrow, high-speed fluid jet of sufficient velocity to penetrate skin and tissue.
Needle-free jet injection using real-time controlled linear Lorentz-force actuators (Andrew Taberner, N. Catherine Hogan, Ian W. Hunter)
Are you sick of prodding yourself with needles just to get your B12, insulin, or any other medication? Whether you’re a kid or a tough guy, nobody likes needles. Some people really don’t like needles, to the point where it interferes with their treatment.
Needle phobia is real, and it directly reduces compliance with treatment.
In other words, people who fear needles will often forego their shots. This poses a real risk to our readers, who suffer from pernicious anemia and B12 deficiency. In these cases, not maintaining a consistent daily injection schedule could lead to nerve damage.
Sometimes, it’s not even needle phobia that keeps people out of their daily injection schedule. It could simply be the discomfort of having to do the shots every day. You know, probing the skin for a spot where the tissue is not hardened from previous shots, darting the needle in, and then disposing of this sharp object. Who wants that?
Luckily, it no longer has to be this way.
Welcome to Needleless Injectors
Well, how does a needle-free injection device sound to you? 🙂
Obviously, such a device would be a complete game changer. If you inject daily (as is the case with insulin for diabetics or B12 for pernicious anemia patients), this translates to 30 needles a month, 360 a year, or more than 10,000 needles in 30 years. Imagine all the collective waste and pain that such a needle-free injector would spare.
Needle-free injection technology isn’t new, dating back to the 1940s. However, it has had limited adoption because it was bulky. In the last few years, we’ve been monitoring the progress of needle-free injection devices, hoping one day our readers could use it.
We’re excited to say, this day is here. The technology is now mature.
In order to offer a sweet deal to our readers, we talked to numerous injector brands. The needleless device from Australian brand Comfort-in™ appeared to fit our readers the best, and we’re grateful that the company agreed to cooperate. In fact, adults and kids are already using the device to inject themselves with methyl B12 at home:
Why The Comfort-in™?
When we searched for a needleless injector to recommend to our readers and customers, we were specifically looking for an injector that meets all these requirements:
The Comfort-in™ ticks all these boxes. In contrast, some of the other brands use CO2 gas. One of the brands had its medical certificate revoked. Another uses a fixed-dose of 0.5ml, which completely rules it out for most of our customers. The Comfort-in™ is the simplest and most versatile needleless injector we could find available to the public.
The Comfort-in™ Needleless Syringe
Those who are familiar with needle-free technology will be aware that in the last two decades, a number of companies around the world declared an interest in developing ‘needle-free’ injector systems. What has happened to them? Some went bankrupt and some couldn’t keep up with supply demands. One sold their jet injector technology to a massive syringe and needle manufacturer who put it on a back shelf, another to a pharmaceutical company requiring a prescription and limited use and availability.
We are proud to stand by our commitment to continue to provide the Comfort-in™ to the general public as well as professionals. We have no intention of selling to syringe or needle companies, or pharmaceutical companies that would restrict your access to this revolutionary product.
Needle-phobia and the discomfort of ongoing needle injections is a real barrier for many people who require ongoing medical care. We are here for those people, whatever their needs may be.
Comfort-in™
The team at Comfort-in™ has revolutionized the playing field, and has built an injection device that fully replaces a needle, and which you can order online and use at home. It’s easy to learn, and it’s 100% painless and doesn’t leave a mess.
If you’re injecting B12 (or insulin, growth hormones, vaccinations – you name it), you can use this needleless syringe to deliver it into your bloodstream, using the narrow jet of the injected liquid instead of a hypodermic needle to penetrate the skin.
It also distributes the medication better, as illustrated here:
Here’s what a needle-free injection looks like compared to a regular injection:
A Revolutionary Experience
We’re excited, because this jet injector is perfect for our injectable methyl-B12 (for which we like daily doses of 0.3ml).
How does it work? The Comfort-in™ injects liquid through the skin, into the subcutaneous tissue via high-pressure, at a speed of 100 meters per second.
This spring-operated, needle-less syringe is ideal for personal use. You can use it to propel any injectable liquid through your skin, in variable doses of up to 0.5ml.
The injector is an internationally certified, registered medical device. It’s safe, and won’t penetrate vital blood vessels.
It’s also durable, and can be used for up to 10,000 injections (30 years, if you inject daily). This makes it the longest lasting needle-free injector that we know of.
All in all, the Comfort-in™ needleless injector is simple, safe, stress-free, needle-free, and most importantly pain-free.
9 Reasons to Use the Comfort-in™
No Pain
Injections are painless, unlike those done with sharp needles.
Not Just B12
You can use it for insulin, dental, cosmetics, IVF, and other injectable liquids.
Simple
Very safe and extremely easy to use, even for kids or on dogs.
No Tissue Damage
No skin or scar tissue damage, like with regular needle injections.
No Fear
Reduces the psychological inhibitions associated with needles.
Reliable
Requires no batteries or gas replacements, and will work up to 10,000 shots.
No Stress
Eliminates injection-induced stress, such as with normal shots.
No Injuries
No infections from needle sticks to either the patient or the physician.
Cost Effective
Cheaper than regular syringes and needles over the long term.
What Can You Use It For?
The Comfort-in™ is the most versatile needless syringe for the subcutaneous delivery of medication (it has an intramuscular version as well if you need) that we know of.
You can use it for almost any type of injectable:
Vitamin B12
Use the device to inject our methyl B12.
In-Vitro Fertilization
Couples undergoing IVF can use it to inject.
Sport Medicine
Ideal in treatments like peptide injections.
Other Vitamins
Not just B12. You can use it for any vitamin.
Hormone Therapy
Inject testosterone or growth hormone.
Vaccines
Use the intramuscular kit to inject vaccines.
Diabetes (Insulin)
Needleless insulin shots are a reality now.
Erectile Dysfunction
Men with ED can also use the device to inject.
Veterinary Shots
Useful for injecting to pets, who can’t sit still.
In addition to home users, professionals who are currently giving injections with a traditional syringe and needle from a multi-dose vial can also use the Comfort-in™. This injector possesses ISO Ec, TGA, and CE certifications, classifying it as a medical device suitable for unrestricted use with all types of liquid medications.
While other jet injectors offer limited control, curtailing their applicability, the Comfort-in™ provides excellent control over jet parameters, including speed and dose.
This makes it a very versatile needleless syringe.
Again, How Does It Work?
The liquid itself acts as the needle
We know, it sounds crazy. But it’s really simple:
The Comfort-in™ injects liquid drugs through the skin, without needles. You first draw your desired injectable liquid into the device. You do so by using an adapter that comes with the device. You can fill the nozzle with up to 0.5ml of injectable liquid.
Then, you load the injector using the lever that comes in the package. You press the button, and the liquid medication in the needleless syringe flows effortlessly as a small jet, into your body via a spring-action – at the speed of 100 meters per second. The liquid medication then disperses into the subcutaneous tissue, in a cone-like shape.
How to Inject Our Methyl-B12 With The Comfort-in™?
You’ll get instructions with your kit, but here are general guidelines:
1. Attach the adapter to the B12 vial.
2. Turn the vial upside down, and draw the B12 into the syringe.
3. Load the device with the pressure lever, until you hear a click sound.
4. Rotate the head of the injector until it reveals your required dose.
5. Screw the filled syringe into the head of the injector.
6. Press the syringe against your skin and click the button.
* You can keep the B12 vial refrigerated (wrapped in aluminum foil, as we always recommend, to prevent photolysis), with the adapter attached.
No More Needle Phobia
Just how bad do people fear needles? Patients often show up, who have never been vaccinated since childhood because of needle anxiety. In fact, clinics report that some of them ask for general anesthesia before simple shots. One picture is worth a thousand words, so look at this image, where a person passed out before a shot was given:
Needle-phobia is real, and the discomfort of ongoing needle injections is a real barrier for many people who require ongoing medical care. Needle-free injectors provide such people with a phobia-free injection solution. This directly links with compliance, because many of those who fear needles will simply skip their daily injections.
This problem isn’t small at all:
As much as 25% of adults and up to 75% of children have needle-phobia.
Again, it causes patients to delay treatment or forego it altogether. Physicians are left in an awkward position. Parents are left with a tough question; inflict pain and fear to the child, or skip the medication for today? (tomorrow comes the same question.)
If you are squeamish, have a fear of needles, and need to self-inject frequently, this kind of technology can help you overcome your phobia. The Comfort-in™️ is an astonishing device, in a way that it is giving needle-phobic people the confidence to self-administer life-saving medications via a needle free injection system. It is a game-changer.
Needleless injectors are pain-free, fear-free, risk-free, and stress-free.
Prevent Your Skin From Hardening
With the Comfort-in™️, no sharp needles will pierce through your delicate skin. This reduces the likelihood of tissue damage and the formation of scar tissue. It also reduces the chance of developing lipohypertrophy – small dents or lumps of fatty tissue under the skin, which is caused by repeated injections in the same place.
When you use needles for injections, your skin tissue can harden over time. This is why we suggest alternating the injection sites (in our B12 injection instructions). In contrast, injections with jet-injectors preserve tissue and prevent lipohypertrophy.
No More Needle Injuries
The Centers for Disease Control and Prevention estimates that hospital-based health care workers accidentally prick themselves with needles 385,000 times each year.
Jet injectors like Comfort-in™ can help reduce these injuries, and needleless injecting can also lower the risk of contracting diseases like HIV and skin infections.
For home users, the absence of needles is especially beneficial when administering shots to children or pets who can’t keep still. This is another reason why veterinarians find needleless syringes invaluable, as they often deal with restless animals.
Overall, this device greatly simplifies the process of administering injections.
Needle-Free Methyl B12 Injections
Methylcobalamin is one of the two active forms of B12. Its superb utility comes from both increasing B12 levels and reducing homocysteine simultaneously. Thus, for many patients it solves two problems at once. It generates S-adenosyl methionine, the most crucial methyl donor we have, further helping the body in vital processes.
Therefore, methyl B12 is considered the ultimate form of B12. It is easiest to absorb, and it can even fully reverse symptoms. If you’re struggling with neurological symptoms, methyl B12 is often the only promising treatment for regenerating nerves.
B12 deficiency and pernicious anemia are our areas of expertise. Many of our readers have to inject B12 daily for life, and the Comfort-in™ can boost their life quality, which is why we’re excited about this needleless syringe. In fact, the injection of methyl B12 has become one of the more popular uses of the device, according to the company.
However, the benefits of methyl B12 are not limited to just patients with B12 deficiency or pernicious anemia. For example, it is a godsend to kids with special needs:
Due to their methylation issues, children on the autistic spectrum have experienced stark cognitive improvements with the use of methyl B12 shots. These kids tend to do well on methylcobalamin but worse on other forms, like cyanocobalamin. There’s a wealth of anecdotal and professional opinion on the use of methyl B12 in such cases.
There are also many studies on the effectiveness of methyl B12 on improved function in a plethora of conditions, which you can read about in our article about B12 forms.
When it comes to B12 shots and children, a key problem that parents and physicians report is the physical administering of the shots themselves. That is, if you want the B12 to do its job and stabilize the behavior and brain function of your child, your child must first comply with the shots. Of course, easier said than done.
This is where the Comfort-in™ needle-free syringe comes to help.
Let Children Be Children
It’s already traumatic for children to know that they suffer from a condition that makes them different from the rest of their friends. The traditional way of injecting – that is, pricking with needles – can be overwhelming and aggravate the child’s mental state. This is why parents and professionals use techniques such as calming or distracting the child, singing nursery rhymes, or playing soothing music when giving a shot.
Imagine having to go through it every day.
The ordeal of injections can also strain the parent-child relationship. There are reports of kids becoming distressed at seeing the signs of an impending injection, such as a parent preparing to hold their hand. This is because the child begins associating these things with the shots themselves. The trauma can be so overwhelming that parents frequently delay treatment until the child is older, or stop the treatment altogether.
In the case of B12, stopping the treatment can be catastrophic.
Some parents have reported trying anesthetic creams at the injection site. Some have tried giving injections to their children while they are asleep, though this raises concerns about trust and consent which could impact the development of their relationship.
Jet injectors like the Comfort-in™ make injections for children simple, safe, stress-free, needle-free, and pain-free. In fact, kids can easily self-administer the shots. Of course, as mentioned, this practical solution can be used for more than just B12. Even their vaccinations could be made more pleasant thanks to a needle-free experience.
For Insulin & Other Injectables Too
Our readers primarily deal with B12 deficiency, but many also suffer from co-existing conditions, such as diabetes. The Comfort-in™ also lets you inject insulin, which is why the injector comes with one adapter for our B12 vials, and another for insulin pens.
Two birds with one stone.
In fact, you can use the Comfort-in™ needleless device for a variety of drugs. Insulin and B12 are just the most common uses among our readers.
Speaking of diabetes, Comfort-in™ reports having demonstrated in the Diabetes Control and Complications Trial its ability to reduce post-meal hyperglycemic peaks better than an insulin pen, without increase or sudden decrease in hyperglycemic episodes.
In a fraction of a second, the needleless injector will push the insulin with precisely measured pressure, into the tissue below the skin. As with injecting B12, it is painless, tissue-preserving, and doesn’t carry the risk of needle-stick injuries or infections.
The Comfort-in™ needleless injector has revolutionized patient comfort by eliminating the need to use painful needles in cases of diabetes (or B12 deficiency). The use of needle-free injectors in diabetes is very effective in enhancing compliance with therapy, especially when multiple daily doses of insulin are required.
The discomfort of needle shots belongs to the past. If you’ve had to inject insulin several times a day for a long time, the Comfort-in™ will give you a new life.
For Pets With Diabetes As Well
The Comfort-in™ can also serve as an insulin autoinjector for dogs or other pets. Given that pets can be quite active, injecting them with needles has always been challenging. With this device, the process becomes much easier, and they won’t feel a thing.
It’s Worth Investing In a Needleless Injector If You…
Dread Needles
You don’t like piercing your skin with needles.
Inject to a Pet
Needle-free shots are easier for the dog.
Inject to a Child
You want to remove the fear factor entirely.
Worry About Infections
Unsterilized needles are a problem in many areas.
Need Daily Injections
You have to go through the hassle daily.
Dislike Scar Tissue
You don’t want your skin hardening from needles.
FREE Worldwide Shipping For Us
When you order directly from Comfort-in’s™ website, the EMS shipping fee is usually 30 Australian dollars. However, we’ve secured a special deal for our readers: free shipping! To take advantage of this offer, place your order through our website.
- International Shipping (All Countries)
- Tracking Code
- 100% Free
Note: Delivery usually takes up to a week.
Order Your Comfort-in™ Now
Comfort-in™ ships your kit with a set of universal Luer adapters, compatible with our methyl-B12 vials as well as other injectable containers. The kits do not come pre-filled with B12 – you can order it separately here. You can get the saline here.
The four options below are a one-off purchase, NOT a subscription:
Subcutaneous Kit
The Comfort-in™ with a spring calibrated to inject into subcutaneous tissue. $285- In stock
- SQ Comfort-in™ Injector
- Comfort-in™ Pressure Lever
- Portable Pouch
- 10 Sterilized Nozzles
- Luer Adapters For Any Liquid
- Instructional Manual
- Free Worldwide Shipping
Subcutaneous Kit + Refills
The same Comfort-in™ for subcutaneous delivery, but with 50 extra disposable nozzles. $345- In stock
- SQ Comfort-in™ Injector
- Comfort-in™ Pressure Lever
- Portable Pouch
- 10 Sterilized Nozzles (+50 Extra)
- Luer Adapters For Any Liquid
- Instructional Manual
- Free Worldwide Shipping
Intramuscular Kit
The Comfort-in™ with a spring calibrated to inject into intramuscular tissue. $320- In stock
- IM Comfort-in™ Injector
- Comfort-in™ Pressure Lever
- Portable Pouch
- 10 Sterilized Nozzles
- Luer Adapters For Any Liquid
- Instructional Manual
- Free Worldwide Shipping
Intramuscular Kit + Refills
The same Comfort-in™ for intramuscular delivery, but with 50 extra disposable nozzles. $380- In stock
- IM Comfort-in™ Injector
- Comfort-in™ Pressure Lever
- Portable Pouch
- 10 Sterilized Nozzles (+50 Extra)
- Luer Adapters For Any Liquid
- Instructional Manual
- Free Worldwide Shipping
Adapters & Disposables For The Comfort-in™
When the need arises, you can order more needleless nozzles and adapters here:
50 Disposable Nozzles
Syringes that can hold up to 0.5ml, with a plunger to discharge it through a micro-orifice at the tip.
30 Luer Adapters
Attach a needle to these universal adapters and you can use them with any type of container.
30 Pen Adapters
Designed to facilitate the transfer of medicine from pen cartridges, such as insulin for diabetics.
50 Flat Positioning Caps
If you’re very thin, these caps will soften the pressure when an injection is pressed against the body and released.
100% Money-Back Guarantee
There’s no risk. If you’re not completely satisfied with the needleless injector, simply send it back within 30 days for a full refund, no questions asked.
Frequently Asked Questions
If you have questions regarding the Comfort-in™ needleless injector, please review this FAQ section. If you still can’t find an answer, don’t hesitate to reach out to us.
Summary
Skipped all the way to the end? 😉
In needle-less injections, a specialized device propels an injectable substance (such as insulin, hormones, or B12, in our case) through the skin. This process combines pressure, high-velocity, and a specially designed nozzle. As no needles are involved, this approach entirely eliminates both the pain and fear associated with traditional injections.
The Comfort-in™ is the most versatile needle-free jet injection system available. Its use extends to a variety of applications – from B12 and insulin to dental care, growth hormones, erectile dysfunction (ED) treatments, IVF procedures, allergy shots, and more. Moreover, it allows for both subcutaneous and intramuscular injections.
Given that our readers regularly inject B12, we’ve partnered with Comfort-in™ to offer their device here, with an exclusive offer of free worldwide shipping.