It’s not only pernicious anemia patients who buy our injectable B12. We have many repeat customers with other diseases who benefit from methylcobalamin just as well. Not surprisingly, the most common question we get from both groups is, just how quickly do B12 shots work? Simply put, how soon do you feel less tired after a B12 injection?
Here’s our answer.
How Long For B12 Shots to Work?
We know how challenging it is to be B12 deficient. Even small daily chores leave you sore and breathless. You have trouble remembering things. You’re always tired, and often find yourself having to go to sleep. You are literally sick of being sick. Even worse, loved ones don’t understand why you’re so exhausted all the time. They can’t understand.
In other words, we can’t blame you for wanting the shots to take effect ASAP.
So, how long does it take for B12 injections to work? Well, people do seem to react differently. Some patients report a stark increase in energy within days, while others report slower progress. Here’s the most crucial thing to keep in mind:
Within the first 48-72 hours, the B12 shots will lead to a rapid increase of immature red blood cells (reticulocytes), and the subsequent, gradual correction of anemia.
But full correction may take up to 3 months.
This is because methylcobalamin B12 acts on the bone marrow to normalize red blood cell formation. The life cycle of a red blood cell is 90 days, so you will not reach your optimal improvement until after 90 days, when all malformed red blood cells have died off. So, inject daily for at least three months, and only then gauge how you feel.
Knowing How Quickly B12 Shots Work…
Remember, it can take years to become deficient in B12. Therefore, it shouldn’t surprise you that it takes more than just a few weeks to fix a deficiency and correct the resulting anemia. Give the shots some time, and you’ll feel like a new person.
… Keep Injecting.
If you’re battling pernicious anemia or another type of severe B12 deficiency, remember that it is crucial to keep injecting. Besides the anemia, a prolonged lack of B12 could lead to serious neurological damage, even paralysis. By injecting daily, you’ll at least ensure that you won’t be getting worse. So, how quickly do B12 injections work? Give them at least 90 days, and see how you feel. Hopefully things will get better.
All the best.